この手首式発振器はジメチルシリコーン油の消泡性能を専門に設計、試験し、米国薬局方の要求に符合する。
この手首式発振器はジメチルシリコーン油の消泡性能を専門に設計、試験し、米国薬局方の要求に符合する。
技術パラメータ:
距離:13.3 cm
コンテナ数:2 x 2
周波数:300 rpm
振幅:0-15 o調整可能
タイマー(オプション):0.01 s-99.99 min
外形寸法:55 x 40 x 32 cm
附:ジメチルシリコーン油(Simethicone)の消泡性米国薬局方試験方法
Defoaming Activity
Foaming solution: 10 mg/mL of octoxynol 9 in water
Sample solution: 4 mg/mL of Simethicone in tertiary butyl alcohol. Shake vigorously.[Note—Warm slightly, if necessary, to dissolve. ]
Analysis
[Note—For each test, use a clean, unused, 250-mL glass jar. ]
Add, dropwise, 500 μL of the Sample solution to a clean, unused, cylindrical 250-mL glass jar, fitted with a 50-mm cap, containing 100 mL of the Foaming solution. Cap the jar, and clamp it in an upright position on a wrist-action shaker. Using a radius of 13.3 ± 0.4 cm (measured from the center of the shaft to the center of the bottle), shake for 10 s through an arc of 10 at a frequency of 300 ± 30 strokes/min. Record the time required for the foam to collapse. The time, in s, for foam collapse is determined at the instant the first portion of foam-free liquid surface appears, measured from the end of the shaking period.
Acceptance criteria: The defoaming activity time does not exceed 15 s.